Portfolio

Fasmatech offers design services and custom engineering solutions of integrated instrumentation platforms to academic and research institutes for applied and fundamental research. The extensive portfolio of technological solutions available to address a diverse set of analytical problems includes:

• Ionization sources (ESI, APPI, LDI, PTR, EI)
• Gas dynamically optimized fore-vacuum ion optics
• Radio-frequency ion guides & collision cells
• Ion trapping technology
• Re ectron time-of-flight mass analyzers
• Ion mobility spectrometers

Performance Achievements

• Multiply charged radical ions formed by electron irradiation of MALDI ions stored in a novel linear ion trap
• Enhanced CID efficiency in rectangular RF trapping fields
• Sensitivity in the low amol range

Multiply charged radical ions formed by electron irradiation of insulin-B ions generated by MALDI.

Slow Heating CID of coronene – single carbon atom loss.

Ion guides utilize radio frequency electric elds for radial con nement and are applied extensively for transportation, thermalization, gating and collisional dissociation of ions. Fasmatech’s novel hybrid RF ion guide is designed to compress phase space progressively to enhance acceptance and deliver a highly collimated ion beam. Segmentation guarantees operation over an extended range of pressures and the formation of mononergetic ion beams.

Simulated trajectories demonstrating progressive radial compression of an ion beam moving from higher- to lower-order multipole fields.

Aerolens optics are designed to suppress turbulence and control the extent of ion diffusion at intermediate pressure. Laminarization of the supersonic jet in API interfaces enhances ion transmission and extends the operating pressure range of conventional ion funnel optics. Enlarged inlet openings can be employed leading to improved sampling efficiency.

Transitions of the supersonic jet inside the aerolens to ultimately form a steady-state laminar flow.

RF transfer lines are designed to receive and selectively inject ions from an ionization source to a reaction chamber or into an ion trap, for example the Omnitrap™. Mass selection is performed with a quadrupole mass filter equipped with an off-axis detector. On-axis transmission and off-axis detection are supported by fast switching electronics. The transfer line accommodates Fasmatech’s intermediate pressure ion optical solutions including a hybrid RF ion guide and a temperature-controlled ion funnel.

Monodisperse nanoparticles generated by spark-discharge enable the evaluation and optimization of the gas dynamical properties of fore-vacuum ion optics. Laser diagnostics are combined with state of the art DSMC computations, RANS-sst modeling and ion tracing algorithms for in depth characterization of ion optical components immersed in fast gas flows.