RF transfer lines are designed to receive and selectively inject ions from an ionization source to a reaction chamber, into an ion trap or a TOF mass analyzer. Quadrupole mass filters can be integrated including an off-axis detector. On-axis transmission and off-axis detection are supported by fast switching electronics. The RF transfer lines offered by Fasmatech include unique ion optical solutions to support operation over an extended range of pressures and highly efficient gating techniques for storing, accumulating and releasing ions.